Overview
Hepatitis B is a liver infection caused by the hepatitis B virus (HBV). Testing includes multiple markers to determine immunity from vaccination, acute infection, or chronic infection. The vaccine has been routine since 1991, but many adults remain unvaccinated.
Who Should Get Tested?
All pregnant women, people from regions with high HBV prevalence, injection drug users, men who have sex with men, HIV-positive individuals, and anyone requesting STI screening.
What to Expect
Standard blood draw. Multiple markers may be tested to determine immunity status vs active infection.
How to Prepare
No special preparation. Blood draw for surface antigen and surface antibody testing.
Window Period (When to Test)
Earliest Detection: 21 days post-exposure
Optimal Testing: 60 days post-exposure
Conclusive Results: 90 days post-exposure
HBsAg detectable 1-9 weeks post-exposure; antibodies take 2-12 weeks to develop.
Symptoms
In Men
Often asymptomatic; possible jaundice, fatigue, abdominal pain, nausea, dark urine
In Women
Same as male - often asymptomatic, especially in chronic cases
Possible Complications
Cirrhosis, liver cancer, liver failure, chronic infection (5-10% of adults)
Treatment
Acute: supportive care. Chronic: antivirals (tenofovir, entecavir) suppress virus; vaccine prevents infection
Retesting Recommendations
If immune, no retest needed. If susceptible, get vaccinated. If infected, regular monitoring required
Frequently Asked Questions
Cost & Pricing
The Hepatitis B Test typically costs between $49 and $89 when ordered directly through a certified lab. Prices may vary by location. Many testing centers accept HSA/FSA cards.
Learn More: Visit the CDC Hepatitis B Test Information for additional details from the Centers for Disease Control and Prevention.