Overview
Hepatitis C is a curable liver infection that often becomes chronic without symptoms for decades. The CDC recommends one-time screening for all adults. Modern direct-acting antivirals cure over 95% of infections in 8-12 weeks. Testing is crucial for early detection and treatment.
Who Should Get Tested?
All adults 18+ (CDC universal recommendation), pregnant women, anyone with history of injection drug use, those born 1945-1965, HIV-positive individuals, and anyone with abnormal liver enzymes.
What to Expect
Initial blood draw for antibody test. If positive, automatic reflex to HCV RNA test to confirm current infection. Results in 1-2 days.
How to Prepare
No preparation needed. Blood draw for antibody testing; positive results require confirmatory HCV RNA test.
Window Period (When to Test)
Earliest Detection: 28 days post-exposure
Optimal Testing: 42 days post-exposure
Conclusive Results: 90 days post-exposure
Antibodies typically detectable 4-10 weeks post-exposure; HCV RNA detectable 1-2 weeks earlier.
Symptoms
In Men
Usually asymptomatic for years; possible fatigue, jaundice, abdominal pain in advanced disease
In Women
Same as male - typically asymptomatic until liver damage occurs
Possible Complications
Cirrhosis, liver cancer, liver failure (develops over 20-30 years in 15-30% of chronic infections)
Treatment
Highly curable with 8-12 weeks of oral direct-acting antivirals (sofosbuvir/velpatasvir, etc.)
Retesting Recommendations
Once cured or if antibody-negative, test based on ongoing risk factors
Frequently Asked Questions
Cost & Pricing
The Hepatitis C Test typically costs between $49 and $99 when ordered directly through a certified lab. Prices may vary by location. Many testing centers accept HSA/FSA cards.
Learn More: Visit the CDC Hepatitis C Test Information for additional details from the Centers for Disease Control and Prevention.