Mycoplasma Genitalium Test

Overview

Mycoplasma genitalium (M. gen) is an emerging STI that often goes undetected. It causes urethritis in men and cervicitis/PID in women. NAAT testing is required as it cannot be cultured. Growing antibiotic resistance makes proper testing and treatment essential.

Who Should Get Tested?

Those with persistent urethritis/cervicitis despite negative chlamydia/gonorrhea tests, PID cases, and those with persistent STI symptoms of unknown cause.

What to Expect

Urine sample or swab collection. Not all labs offer testing; may need to request specifically.

How to Prepare

First-catch urine (do not urinate 1-2 hours before) or genital swab. No antibiotics for 3-4 weeks prior if possible.

Window Period (When to Test)

Earliest Detection: 7 days post-exposure

Optimal Testing: 14 days post-exposure

Conclusive Results: 21 days post-exposure

Limited data on exact window period; testing available within 2-3 weeks of suspected exposure.

Symptoms

In Men

Urethral discharge, burning with urination, persistent urethritis despite negative standard tests

In Women

Vaginal discharge, bleeding after sex, pelvic pain, cervicitis, PID

Possible Complications

PID, infertility, urethritis complications, increased HIV transmission risk

Treatment

Antibiotics (azithromycin or moxifloxacin); macrolide resistance testing increasingly important

Retesting Recommendations

Test of cure recommended 3-4 weeks after treatment due to resistance concerns

Frequently Asked Questions

How common is Mycoplasma genitalium?

More common than gonorrhea, affecting 1-3% of sexually active adults. Many cases are asymptomatic or misattributed to other causes.

Is Mycoplasma genitalium curable?

Yes, but antibiotic resistance is increasing. Treatment typically requires azithromycin or moxifloxacin after testing for resistance markers.

Why isn't Mycoplasma tested routinely?

Testing is more complex and expensive than for chlamydia/gonorrhea. Routine screening isn't recommended, but testing is important for those with persistent symptoms.

Can Mycoplasma cause infertility?

Yes, like chlamydia and gonorrhea, M. gen can cause PID in women and epididymitis in men, potentially leading to fertility problems.

Cost & Pricing

The Mycoplasma Genitalium Test typically costs between $79 and $149 when ordered directly through a certified lab. Prices may vary by location. Many testing centers accept HSA/FSA cards.

Learn More: Visit the CDC Mycoplasma Genitalium Test Information for additional details from the Centers for Disease Control and Prevention.

Medical Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.